About

In just two minutes, the CelTivity system captures intracellular data from the biopsy and creates dynamic cell images of the tissue samples to identify and interpret the presence of different types of cells, such as cancer, non-cancer and granuloma, to name a few.

• Cambridge, Massachusetts, United States
• Bertrand Le Conte de Poly, Claude Boccara
• https://www.aquyre.com/
• 2013

About

Cordio has developed a monitoring solution for Congestive Heart Failure (CHF) patients using only a patient's speech, sampled via a mobile device. The system, Cordio HearO®, can sense fluid accumulation and allow health care professionals to manage their CHF patients remotely. Cordio HearO™ is easy to use, non-invasive CHF monitoring device with great patient compliance. 

Cordio's product is patient-dependent (i.e., each patient serves as his or her own baseline) and language independent. It is comprised of a recording application operating on a patient device such as mobile devices, computer, Alexa device, (etc.), with an analysis software operating on the cloud. During monitoring, samples of the patient's speech are analyzed and compared to the model, measuring the differences which are characterized as the target disorder.

• Tel Aviv, Israel
• CEO: Tamir Tal
• https://cordio-med.com
• 2013

About

DermaSensor, Inc. has commercialized the first FDA cleared, automated device that provides an objective skin cancer risk result to American’s one million physicians who are not already experts in assessing patients for skin cancer (e.g. family doctors, internal medicine doctors, gynecologists). The DermaSensor™ device enables these physicians to non-invasively and effectively test lesions for all common types of skin cancer, specifically melanoma, basal cell carcinoma, and squamous cell carcinoma. The patented spectroscopy technology utilized in their handheld device has a published sensitivity of 95.5% from their FDA pivotal study with over 1,000 patients and uses a simple 0-10 malignancy risk level scale to improve physicians’ management of suspicious lesions. Literature shows that primary care physicians' sensitivity for correctly referring cancerous moles is as low as 54%.

• Miami, Florida, United States
• CEO: Cody Simmons
• https://dermasensor.com/
• 2009

About

Insightec Ltd. is a global healthcare company that has developed, created, and manufactures the next generation of patient care by mastering the therapeutic power of acoustic energy. The Company has pioneered a treatment that uses Magnetic Resonance Imaging (MRI) guided focused ultrasound to provide incisionless, outpatient neurofunctional brain treatment for patients with medication-refractory Essential Tremor, medication refractory unilateral tremor-dominant Parkinson's Disease and for the management of moderate to severe unilateral advanced Parkinson's Disease medication refractory motor complications.

The Company is pursuing innovations to address other neurological conditions including, but not limited to, epilepsy, primary and metastatic brain cancer, Alzheimer’s Disease, addiction, and ALS. Research for these potential future applications is in various stages of development, including partnerships with leading academic and medical institutions. Insightec is headquartered in Haifa, Israel and Miami, with offices in Tel Aviv, Dallas, Shanghai, and Tokyo.

• Tirat Carmel, Hefa, Israel
• CEO: Dr. Maurice R. Ferre
• https://www.insightec.com/us
• 1999

About

Transforming surgery with its proprietary surgical robotic technology. Momentis has set out to surpass today’s best solutions through: better clinical outcomes, reduced footprint, versatility, and cost.
They are the first robotic solution to receive FDA authorization for transvaginal gynecological procedures.

The Anovo™ Surgical System features unique robotic instrument ARMS that mimic the movement of the surgeon’s shoulder, elbow and wrist, offering high dexterity, multi-planar flexibility and unprecedented articulation. The ability to articulate the ARMS enables the transvaginal approach to benign gynecologic procedures and surgeons are able to use the familiar fundus to cervix technique without the need for multiple abdominal incisions. Anovo requires a much smaller footprint and costs significantly less than conventional robotic systems, making it possible for more hospitals and ambulatory surgery centers to acquire the system.

• Tel Aviv, Israel
• Dvir Cohen
• https://www.momentissurgical.com/
• 2013

About

Leader in the digital evolution of musculoskeletal care and sensor technology for total joint replacement. OrthoSensor quantifies orthopedics through intelligent devices and data services that allow surgeons and hospitals to deliver evidence-based treatments.

• Dania, Florida, United States
• Martin Roche, Steve Seger
• https://orthosensor.com
• 2006

About

PathologyWatch offers a fully integrated digital pathology solution to Dermatologist and believes that it is an emerging leader in the deep learning / artificial intelligence segment of the market. PathologyWatch has integrated laboratory information systems, scanners, digital viewer technology, and EMRs into an end-to-end solution for dermatologists.

SONIC purchased Pathology Watch in 2023 for $150m.

• Utah, USA
• Dan Lambert
• https://pathologywatch.com
• 2012

About

Accuryn addresses a critical unmet need with respect to kidney functioning monitoring by offering a comprehensive solution that significantly enhances patient care and hospital efficiency. The Accuryn Monitoring System has the ability to detect and enable earlier intervention in Acute Kidney Injury (AKI) as much as 33 hours ahead of the current standard of care that relies on a Serum Creatinine (SCr) blood test, based on KDIGO. This early detection capability may improve patient outcomes, reduce the costs incurred by hospitals, with the potential of becoming a critical tool in the management of AKI.

• Heyward, CA, United States
• CEO: Todd Dunn
• https://accuryn.com
• 2011

About

* The firm acted as placement agent in each of these transactions. This list includes all deals from 2020 forward and is presented in alphabetical order. The inclusion of a deal on this list does not imply performance success or guarantee future results. Past offerings are not indicative of future investment opportunities or outcomes. Transactions listed here do not constitute an offer to buy or sell securities.

* The inclusion of a deal on this list does not imply performance success or guarantee future results. Past offerings are not indicative of future investment opportunities or outcomes. Transactions listed here do not constitute an offer to buy or sell securities.

• Manchester, New Hampshire, United States
• Bryan Lord
• https://pristinesurgical.com
• 2013

About

TriFlo Cardiovascular is a biotechnology firm working in stealth mode.

• Huntington Beach, California, United States
• NA
• https://triflocv.com/
• 2017

About

TriSalus Life Sciences® is an oncology focused medical technology business providing disruptive drug delivery technology with the goal of improving therapeutic delivery to solid tumors. The Company’s platform includes devices that utilize a proprietary drug delivery technology and a clinical stage investigational immunotherapy. The Company’s two FDA-cleared devices use its proprietary Pressure-Enabled Drug Delivery™ (PEDD™) approach to deliver a range of therapeutics: the TriNav® Infusion System for hepatic arterial infusion of liver tumors as well as other solid tumors and the Pancreatic Retrograde Venous Infusion System for pancreatic tumors. PEDD is a novel delivery approach designed to address the anatomic limitations of infusion into solid tumors. Nelitolimod delivered by PEDD will be studied across several indications in an effort to address immune dysfunction and overcome drug delivery barriers in the liver and pancreas. TriSalus is publicly traded on NASDAQ: TLSI.

• Westminster, Colorado, United States
• CEO: Mary Sezla
• https://trisaluslifesci.com
• 2009

About

$10-20mm Series A Round (pre-money $40mm): Wesper is a disruptive medical device company in the sleep tech space that brings the full cycle of sleep therapy into the home through the use of a proprietary, state-of-the-art smart patch that delivers results with no wires or complicated set up.

• New York, New York, United States
• Amir Reuveny
• https://wesper.co
• 2017